William D Foulkes Selected Research

Ribonuclease III (RNase III)

6/2017	Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma.
7/2014	Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.
4/2013	Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
1/2012	Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.
1/2011	DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.

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William D Foulkes Research Topics

Disease

102	Neoplasms (Cancer) 10/2022 - 12/2002
73	Breast Neoplasms (Breast Cancer) 10/2022 - 10/2002
21	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 11/2003
10	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 12/2002
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 02/2002
6	Adenocarcinoma 01/2021 - 09/2005
4	Fallopian Tube Neoplasms 01/2022 - 07/2006
4	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 06/2017
4	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2021 - 04/2006
4	Small Cell Carcinoma 05/2019 - 04/2015
4	Carcinoma (Carcinomatosis) 01/2018 - 04/2007
4	Pleuropulmonary blastoma 01/2018 - 01/2011
4	Neoplasm Metastasis (Metastasis) 03/2013 - 04/2009
3	Polyps 09/2021 - 03/2009
3	Triple Negative Breast Neoplasms 01/2019 - 12/2008
3	Endometrial Neoplasms (Endometrial Cancer) 07/2013 - 12/2002
3	Carcinogenesis 01/2011 - 04/2002
3	Colorectal Neoplasms (Colorectal Cancer) 01/2009 - 02/2003
2	Melanoma (Melanoma, Malignant) 01/2022 - 12/2002
2	Dementia (Dementias) 01/2022 - 10/2020
2	Cysts 01/2022 - 01/2018
2	Adenosarcoma 01/2021 - 01/2021
2	Embryonal Rhabdomyosarcoma 01/2021 - 06/2017
2	Familial Breast Cancer 05/2020 - 10/2005
2	Thyroid Neoplasms (Thyroid Cancer) 01/2020 - 12/2016
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2019 - 01/2019
2	Hypersensitivity (Allergy) 01/2019 - 04/2013
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2018 - 01/2018
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2018 - 12/2010
2	medullary Thyroid cancer 01/2018 - 03/2004
2	Second Primary Neoplasms (Neoplasms, Second) 01/2017 - 01/2005
2	Sertoli-Leydig Cell Tumor 07/2016 - 01/2012
2	Candidiasis (Moniliasis) 04/2016 - 07/2014
2	autosomal recessive Candidiasis familial chronic mucocutaneous 04/2016 - 07/2014
2	Adenoma (Adenomas) 01/2006 - 09/2005
2	Squamous Cell Carcinoma of Head and Neck 07/2004 - 04/2002
1	Noninfiltrating Intraductal Carcinoma (DCIS) 10/2022
1	Sex Cord-Gonadal Stromal Tumors (Sex Cord-Stromal Tumor) 01/2022

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2004
19	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 02/2003
18	Estrogen ReceptorsIBA 11/2019 - 10/2002
14	Ribonucleases (Ribonuclease)IBA 01/2022 - 01/2012
12	Tamoxifen FDA LinkGeneric 07/2014 - 10/2002
9	MicroRNAs (MicroRNA)IBA 01/2021 - 11/2011
8	Cyclin D1IBA 01/2020 - 01/2004
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2008
7	Biological ProductsIBA 12/2017 - 04/2003
7	Keratin-5 (Keratin 5)IBA 01/2017 - 10/2003
6	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 08/2008
5	ChromatinIBA 01/2022 - 12/2015
5	Ribonuclease III (RNase III)IBA 06/2017 - 01/2011
5	Hormones (Hormone)IBA 05/2015 - 06/2003
5	Dihydrotachysterol (AT 10)IBA 07/2007 - 10/2003
4	Oral ContraceptivesIBA 01/2022 - 12/2002
4	PlatinumIBA 10/2020 - 01/2006
4	olaparibIBA 01/2020 - 10/2011
4	beta CateninIBA 02/2019 - 01/2004
4	Progesterone Receptors (Progesterone Receptor)IBA 02/2019 - 04/2009
3	RNA (Ribonucleic Acid)IBA 12/2021 - 10/2011
3	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 10/2011
3	Prostate-Specific Antigen (Semenogelase)IBA 12/2019 - 01/2018
3	Cadherins (E-Cadherin)IBA 01/2017 - 05/2005
3	Indicators and Reagents (Reagents)IBA 09/2014 - 09/2009
3	Epidermal Growth Factor (EGF)IBA 09/2014 - 05/2010
3	ErbB Receptors (EGF Receptor)IBA 05/2010 - 10/2008
3	Cyclin EIBA 10/2008 - 02/2004
2	Sucrose (Saccharose)IBA 01/2022 - 11/2016
2	MyogeninIBA 09/2021 - 01/2020
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2020
2	CarcinogensIBA 01/2020 - 03/2009
2	Messenger RNA (mRNA)IBA 01/2020 - 01/2017
2	Pharmaceutical PreparationsIBA 11/2019 - 10/2011
2	Calbindin 2IBA 02/2019 - 05/2015
2	Inhibins (Inhibin)IBA 02/2019 - 05/2015
2	A-Form DNA (A-DNA)IBA 01/2019 - 01/2011
2	Calcibiotic Root Canal SealerIBA 01/2019 - 01/2009
2	imidazole mustard (BIC)IBA 12/2018 - 11/2009
2	Estrogens (Estrogen)FDA Link 01/2018 - 12/2008
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 04/2016 - 07/2014
2	Factor VIII (Coagulation Factor VIII)IBA 06/2012 - 12/2011
2	EndoribonucleasesIBA 01/2012 - 01/2011
2	Phenobarbital (Luminal)FDA Link 01/2011 - 12/2010
2	AntralIBA 01/2006 - 09/2005
2	ORALIT (ORS)IBA 10/2005 - 12/2003
1	AntigensIBA 01/2022
1	Contraceptive Agents (Contraceptives)IBA 01/2022

Therapy/Procedure

28	Ovariectomy (Oophorectomy) 01/2022 - 06/2004
19	Therapeutics 01/2022 - 04/2002
14	Drug Therapy (Chemotherapy) 10/2021 - 02/2003
11	Mastectomy (Mammectomy) 10/2022 - 06/2004
9	Salpingo-oophorectomy 01/2022 - 07/2006
5	Prophylactic Mastectomy 10/2022 - 08/2005
4	Hormone Replacement Therapy (Therapy, Hormone Replacement) 06/2021 - 07/2013
3	Radiotherapy 01/2017 - 01/2005
3	Adjuvant Chemotherapy 11/2009 - 02/2003
2	Immunotherapy 01/2021 - 01/2020
2	Gynecologic Surgical Procedures (Gynecologic Surgery) 12/2008 - 11/2003
2	Chemoprevention 05/2008 - 02/2002
2	Colectomy 01/2006 - 09/2005
1	Intrauterine Devices (Intrauterine Device) 01/2022